What is the function of juxtaglomerular apparatus?
The juxtaglomerular apparatus functions to maintain blood pressure and to act as a quality control mechanism to ensure proper glomerular flow rate and efficient sodium reabsorption. The urethra extends from the bladder to the surface of the body. It consists of an epithelium-lined lumen and a smooth muscle layer.
What is the function of Juxtaglomerular granular cells?
Juxtaglomerular cells (JG cells), also known as granular cells are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) that deliver blood to the glomerulus.
What is the main function of mesangial cells in juxtaglomerular apparatus JGA )?
Extraglomerular mesangial cells are located in the junction between the afferent and efferent arterioles. These cells have a contractile property similar to vascular smooth muscles and thus play a role in “regulating GFR” by altering the vessel diameter. Renin is also found in these cells.
What are the 3 components of the Juxtaglomerular?
The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP].
What is JGA apparatus?
The juxtaglomerular apparatus is the location of renin-secreting cells and the macula densa and lies at the junction between the loop of Henle and the distal nephron at which the tubule comes in close proximity to the afferent arteriole.16.
How JGA is regulating the kidney function?
Regulation involving Juxtaglomerular Apparatus: In kidneys, the JGA acts as a Multi Hormonal renin angiotensin aldosterone system (RAAS). When the glomerular blood flow decreases JG cells activates and releases renin. Renin converts angiotensin in blood to angiotensin 1 and further to angiotensin 2.
What is JGA?
The juxtaglomerular apparatus (JGA), consisting of the glomerular afferent and efferent arterioles and the specialized tubular epithelial cells called the macula densa, plays a central role in the regulation of glomerular hemodynamics and renin release.
What activates Juxtaglomerular cells?
Juxtaglomerular Cells Although they are activated by prostaglandins released from the macula densa cells, they can also release renin independently of the macula densa. Baroreceptors found in the arterioles trigger renin secretion if there is a fall in blood pressure in the arterioles.
What do juxtaglomerular cells secrete?
The juxtaglomerular cells secrete renin, and as specialised smooth muscle cells surrounding the afferent arteriole also have the capacity to affect the perfusion of the glomerulus.
How do you regulate kidney function?
Here are some tips to help keep your kidneys healthy.
- Keep active and fit.
- Control your blood sugar.
- Monitor blood pressure.
- Monitor weight and eat a healthy diet.
- Drink plenty of fluids.
- Don’t smoke.
- Be aware of the amount of OTC pills you take.
- Have your kidney function tested if you’re at high risk.
What is the role of JGA in kidney?
What kind of structure is the juxtaglomerular apparatus?
The juxtaglomerular apparatus is a specialized structure formed by the distal convoluted tubule and the glomerular afferent arteriole.
How does the juxtaglomerular apparatus reduce blood pressure?
In response to elevated sodium, the macula densa cells trigger contraction of the afferent arteriole, reducing flow of blood to the glomerulus and the glomerular filtration rate. The juxtaglomerular cells, derived from smooth muscle cells, of the afferent arteriole secrete renin when blood pressure in the arteriole falls.
Which is part of the juxtaglomerular apparatus secretes renin?
The juxtaglomerular apparatus consists of three types of cells: the macula densa, a part of the distal convoluted tubule of the same nephron juxtaglomerular cells, (also known as granular cells) which secrete renin
Which is collective term for the juxtaglomerular cells in the nephron?
juxtaglomerular apparatus a collective term for the juxtaglomerular cells in a nephron. lacrimal apparatus see lacrimal apparatus. Wangensteen’s apparatus a nasal suction apparatus connected with a duodenal tube for aspirating gas and fluid from stomach and intestine.