What is dabigatran PRADAXA used for?

Dabigatran is used to treat deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in adults and children 3 months of age and older who have been treated with an injectable anticoagulant (‘blood thinner’).

Where is PRADAXA manufacturer?

Announces Updates to Prescribing Information for Pradaxa ® (dabigatran etexilate mesylate) Ridgefield, Conn., April 30, 2013 – Boehringer Ingelheim Pharmaceuticals, Inc.

What are the ingredients in PRADAXA?

Each capsule contains dabigatran etexilate mesylate as the active ingredient: 150 mg dabigatran etexilate (equivalent to 172.95 mg dabigatran etexilate mesylate), 110 mg dabigatran etexilate (equivalent to 126.83 mg dabigatran etexilate mesylate), or 75 mg dabigatran etexilate (equivalent to 86.48 mg dabigatran …

What is the brand name for dabigatran?

Dabigatran is used to prevent blood clots from forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke. Dabigatran is available under the following different brand names: Pradaxa.

Why is dabigatran not used?

[12-19-2012] The U.S. Food and Drug Administration (FDA) is informing health care professionals and the public that the blood thinner (anticoagulant) Pradaxa (dabigatran etexilate mesylate) should not be used to prevent stroke or blood clots (major thromboembolic events) in patients with mechanical heart valves, also …

How long can you stay on Pradaxa?

Treatment continues with two 110mg capsules taken once a day for 28 to 35 days after hip replacement and for 10 days after knee replacement. Treatment is delayed in patients who are still bleeding from the site of surgery. A lower dose is used in patients with moderate kidney problems.

What drugs should not be taken with Pradaxa?

You may have a higher risk of bleeding if you take PRADAXA and:

• aspirin or aspirin-containing products.
• long-term (chronic) use of non-steroidal anti-inflammatory drugs (NSAIDs)
• warfarin sodium.
• a medicine that contains heparin.
• clopidogrel bisulfate.
• prasugrel.

What does Pradaxa do to the body?

Pradaxa (dabigatran) is an anticoagulant that works by blocking the clotting protein thrombin. Pradaxa is used to prevent blood clots from forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke.

Is dabigatran better than warfarin?

Both dabigatran doses were noninferior to warfarin with respect to the primary efficacy outcome of stroke or systemic embolism. In addition, the 150-mg dose of dabigatran was superior to warfarin with respect to stroke or systemic embolism, and the 110-mg dose was superior to warfarin with respect to major bleeding.

Which is the safest Noac?

Real-world Analysis Suggests Apixaban Is Safest of the NOACs, Even for Patients With A-fib.

What are the bad side effects of Pradaxa?

Side effects of Pradaxa include:

• bruising and minor bleeding (such as nosebleeds and bleeding from cuts),
• nausea,
• abdominal or stomach pain,
• stomach upset,
• indigestion,
• heartburn,
• diarrhea,
• skin rash, or.

What foods should you avoid if you are on blood thinners?

5 Things to Avoid If You’re On Blood Thinners

• Leafy greens. Leafy greens like kale, spinach, Brussels sprouts and lettuce contain high amounts of vitamin K.
• Green tea.
• Cranberry juice.
• Grapefruit.
• Alcohol.

What kind of drug is Dabigatran ( Pradaxa )?

Summary: Dabigatran (Pradaxa) is a member of the relatively new class of antithrombotic drugs known as direct thrombin inhibitors (DTIs).

What is the mechanism of action of dabigatran?

Mechanism of Action. Dabigatran (Pradaxa) reversibly binds to the active site on the thrombin molecule, preventing thrombin-mediated activation of coagulation factors.

Can a fixed dosing of dabigatran be adjusted?

Its fixed dosing is not intended to be adjusted on the basis of any coagulation laboratory parameter. In certain clinical situations in which the presence or absence of anticoagulant effect induced by dabigatran needs to be measured, the UW Medicine Dabigatran Assay can be used.

What kind of Medicine is Pradaxa for AFIB?

Boehringer Ingelheim Pharmaceuticals, Inc. What is PRADAXA? Pradaxa ® (dabigatran etexilate) capsules is a prescription blood thinner medicine that lowers the chance of blood clots forming in your body. PRADAXA is used to: